My research concerns the chemistry, metabolism, and biological function of complex glycoconjugates, particularly glycosphingolipids. These compounds play crucial roles in determining cellular properties such as intercellular interactions, recognition, and adhesion. Current research is focused on the following areas:
We are actively investigating treatment strategies for a number of diseases, including Guillain-Barre syndrome that is very much in the news these days. We have developed animal models to test the efficacy of novel therapeutic strategies. We have already achieved considerable success in Phase I for some of the work in rodents--and--we are now entering the phase of non-human primates studies. We are also working on several other neurodegenerative diseases, such as Sanfilippo disease, Alzheimer's disease, Huntington disease, and MS; specifically, from the scientific approach of using stem cell transplantation to achieve tissue repair.
Robert K. Yu, Ph.D., Principal Investigator
list of additional personnel pending...
Revised ]]> January 20, 2010 ]]--> .